Tetrad bubble domain chip arrangement for multiplexing

Rotating magnetic field of bubble domain memory is used to obtain time-division multiplexing of bubble domain circuits into quadrants. Memory bits are assigned on bit-per-chip rather than bit-per-module basis; power is reduced by circulating only portion of bubbles at a time

Redundancy approaches in bubble domain memories

Fabrication of integrated circuit chips to compensate for faulty memory elements is discussed. Procedure for testing chips to determine extent of redundancy and faults is described. Mathematical model to define operation is presented. Schematic circuit diagram of test equipment is provided

Photovoltaic effects in cadmium telluride- mercury telluride heterostructures

Photovoltaic effects in cadmium telluride-mercury telluride heterostructure

L-carnitine reduces the adverse effects of ROS and up-regulates the expression of implantation related genes in in vitro developed mouse embryos

In vitro developed embryos are inevitably exposed to various reactive oxygen species (ROS) which may decrease the embryo's competence in assisted reproductive technology (ART) procedures. Optimization of embryo culture media using antioxidant agents could help to improve embryo quality and could overcome failures in current ART. The aim of this study was to evaluate the effects of L-carnitine (LC), an enhancer of mitochondrial activity and free radical scavenger, in culture media on early embryo competence and expression of ErbB1 and ErbB4 implantation related genes. Two-cell mouse embryos were cultured in the following four conditions: 1. LC group in media containing LC; 2.H 2O2 group exposed to H2O2 for 30 min and then transferred into a simple media; 3.H2O2+LC group exposed to H2O2 for 30 min and then transferred into a simple media containing LC; 4.the control group kept throughout in simple media. All groups were allowed to develop until the blastocyst stage. ErbB1 and ErbB4 expression were evaluated by Real-time PCR and immunocytochemistry. The expression of Sirt3 gene was also evaluated. Intracellular ROS levels were examined by DCFH-DA fluorescence intensity. In order to assess the morphological quality of the embryos, ICM and OCM number blastocyst cells were evaluated by using Hoechst and propidium iodide (PI) staining. ErbB1, ErbB4, ROS levels and cell number were compared across all in vitro groups. Our data reveal that LC significantly increases ErbB1 and ErbB4 gene and protein expression with intracellular ROS levels and Sirt3 gene expression significantly decreased after LC treatment. It is worth noting that an elevated cell number was observed in the LC-treated group compared with the other groups suggesting increased viability and/or proliferation. Our findings suggest that the use of LC could be helpful to improve preimplantation embryo culture media through its effects in decreasing ROS levels and the increase of implantation-related genes. © 2020 Elsevier Inc

Reinforcement Learning for Self Organization and Power Control of Two-Tier Heterogeneous Networks

Self-organizing networks (SONs) can help manage the severe interference in dense heterogeneous networks (HetNets). Given their need to automatically configure power and other settings, machine learning is a promising tool for data-driven decision making in SONs. In this paper, a HetNet is modeled as a dense two-tier network with conventional macrocells overlaid with denser small cells (e.g. femto or pico cells). First, a distributed framework based on multi-agent Markov decision process is proposed that models the power optimization problem in the network. Second, we present a systematic approach for designing a reward function based on the optimization problem. Third, we introduce Q-learning based distributed power allocation algorithm (Q-DPA) as a self-organizing mechanism that enables ongoing transmit power adaptation as new small cells are added to the network. Further, the sample complexity of the Q-DPA algorithm to achieve ϵ-optimality with high probability is provided. We demonstrate, at density of several thousands femtocells per km2, the required quality of service of a macrocell user can be maintained via the proper selection of independent or cooperative learning and appropriate Markov state models

Evaluation of OpenMP for the Cyclops multithreaded architecture

Multithreaded architectures have the potential of tolerating large memory and functional unit latencies and increase resource utilization. The Blue Gene/Cyclops architecture, being developed at the IBM T. J. Watson Research Center, is one such systems that offers massive intra-chip parallelism. Although the BG/C architecture was initially designed to execute specific applications, we believe that it can be effectively used on a broad range of parallel numerical applications. Programming such applications for this unconventional design requires a significant porting effort when using the basic built-in mechanisms for thread management and synchronization. In this paper, we describe the implementation of an OpenMP environment for parallelizing applications, currently under development at the CEPBA-IBM Research Institute, targeting BG/C. The environment is evaluated with a set of simple numerical kernels and a subset of the NAS OpenMP benchmarks. We identify issues that were not initially considered in the design of the BG/C architecture to support a programming model such as OpenMP. We also evaluate features currently offered by the BG/C architecture that should be considered in the implementation of an efficient OpenMP layer for massive intra-chip parallel architectures.Peer ReviewedPostprint (author's final draft

Burden of transport-related injuries in the eastern Mediterranean region: A systematic analysis for the global burden of disease study 2017

Background: Transport-related injuries (TIs) are a substantial public health concern for all regions of the world. The present study quantified the burden of TIs and deaths in the Eastern Mediterranean region (EMR) in 2017 by sex and age.Methods: TIs and deaths were estimated by age, sex, country, and year using Cause of Death Ensemble modelling (CODEm) and DisMod-MR 2.1. Disability-adjusted life years (DALYs), which quantify the total burden of years lost due to premature death or disability, were also estimated per 100000 population. All estimates were reported along with their corresponding 95% uncertainty intervals (UIs).Results: In 2017, there were 5.5 million (UI 4.9-6.2) transport-related incident cases in the EMR - a substantial increase from 1990 (2.8 million; UI 2.5-3.1). The age-standardized incidence rate for the EMR in 2017 was 787 (UI 705.5-876.2) per 100000, which has not changed significantly since 1990 (-0.9%; UI -4.7 to 3). These rates differed remarkably between countries, such that Oman (1303.9; UI 1167.3-1441.5) and Palestine (486.5; UI 434.5-545.9) had the highest and lowest age-standardized incidence rates per 100000, respectively. In 2017, there were 185.3 thousand (UI 170.8-200.6) transport-related fatalities in the EMR - a substantial increase since 1990 (140.4 thousand; UI 118.7-156.9). The age-standardized death rate for the EMR in 2017 was 29.5 (UI 27.1-31.9) per 100000, which was 30.5% lower than that found in 1990 (42.5; UI 36.8-47.3). In 2017, Somalia (54; UI 30-77.4) and Lebanon (7.1; UI 4.8-8.6) had the highest and lowest age-standardized death rates per 100,000, respectively. The age-standardised DALY rate for the EMR in 2017 was 1,528.8 (UI 1412.5-1651.3) per 100000, which was 34.4% lower than that found in 1990 (2,331.3; UI 1,993.1-2,589.9). In 2017, the highest DALY rate was found in Pakistan (3454121; UI 2297890- 4342908) and the lowest was found in Bahrain (8616; UI 7670-9751).Conclusion: The present study shows that while road traffic has become relatively safer (measured by deaths and DALYs per 100000 population), the number of transport-related fatalities in the EMR is growing and needs to be addressed urgently

Kinect-Based Rehabilitation Systems for Stroke Patients: A Scoping Review

Background and Objective. Kinect-based rehabilitation is an effective solution for creating motivation and promoting adherence to rehabilitation programs in stroke patients. The current study was aimed at examining the effects of Kinect-based rehabilitation systems on performance improvement, domains of use, and its limitations for stroke patients. Method. This study was conducted according to Arksey and O'Malley's framework. To investigate the evidence on the effects of Kinect-based rehabilitation, a search was executed in five databases (Web of Science, PubMed, Cochrane Library, Scopus, and IEEE) from 2010 to 2020. Results. Thirty-three articles were finally selected by the inclusion criteria. Most of the studies had been conducted in the US (22%). In terms of the application of Kinect-based rehabilitation for stroke patients, most studies had focused on the rehabilitation of upper extremities (55%), followed by balance (27%). The majority of the studies had developed customized rehabilitation programs (36%) for the rehabilitation of stroke patients. Most of these studies had noted that the simultaneous use of Kinect-based rehabilitation and other physiotherapy methods has a more noticeable effect on performance improvement in patients. Conclusion. The simultaneous application of Kinect-based rehabilitation and other physiotherapy methods has a stronger effect on the performance improvement of stroke patients. Better effects can be achieved by designing Kinect-based rehabilitation programs tailored to the characteristics and abilities of stroke patients